Providing brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study...
View ArticleSecrets of a t-haplotype gene revealed: Decade-long hunt turns up key gene...
The t haplotype in mice—a block of linked genes occupying the proximal half of mouse chromosome 17—is one of the best-studied examples of a selfish genetic element. Through an elaborate sperm-poisoning...
View ArticleScientists identify important regulator for synapse stability and plasticity
(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important...
View ArticleNew 3D hair follicle model to accelerate cure for baldness
Hair loss is a common disorder that affects many men and women due to aging or medical conditions. Current FDA-approved drugs can minimize further hair loss but are unable to regrow new hair. The...
View ArticleA fresh hope for regaining lost hair
Hair loss is usually genetically determined but can also be the result of aging or chronic illness. It is often a distressing condition that negatively affects the self-confidence and social life of...
View ArticleInsulin secretion disrupted by increased fatty acids
Patients with type 2 diabetes have increased levels of circulating glucose and fatty acids, which lead to disease complications. In healthy individuals, β cells within pancreatic islets release insulin...
View ArticleExperimental drug combination selectively destroys lymphoma cells
Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an...
View ArticleWhy cells stick: Phenomenon extends longevity of bonds between cells
Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures,...
View ArticleIlls of aging blood: Short-circuited stem cell programming linked to failing...
As blood stem cells age, changes in the epigenome—the system that regulates which genes are switched on and which are switched off throughout the body—alter these cells in ways that lead to reduced...
View ArticleTackling hearing loss
Some 16 per cent of European adults suffer from hearing loss that is severe enough to adversely affect their daily life. Hearing loss impacts on one's ability to communicate - to hear, process sound,...
View ArticleResearch illuminates molecular mechanism for why stimulating environment may...
"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease. Previous studies have shown that keeping the mind active, exercising and...
View ArticleResearchers design small molecule to disrupt cancer-causing protein
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer. This development could impact...
View ArticleResearchers identify critical link in mammalian odor detection
Researchers at the Monell Center and collaborators have identified a protein that is critical to the ability of mammals to smell. Mice engineered to be lacking the Ggamma13 protein in their olfactory...
View ArticleResearchers shed light on role of genes in autism
(Medical Xpress)—Research carried out by Medical Research Council (MRC) researchers at the University of Oxford has uncovered a chain of genetic events that are common in individuals with autism, and...
View ArticleA first in front line immunity research
Monash University researchers have gained new insight into the early stages of our immune response, providing novel pathways to develop treatments for diseases from multiple sclerosis to cancer.
View ArticleRice team rises to big-data breast cancer challenge
A colorful wheel developed by Rice University bioengineers to visualize protein interactions has won an international competition for novel strategies to study the roots of breast cancer.
View ArticleWhat makes the deadliest form of malaria specific to people?
Researchers have discovered why the parasite that causes the deadliest form of malaria only infects humans.
View ArticleHepatitis C virus: How viral proteins interact in human cells
Scientists at the Helmholtz Zentrum München have for the first time decrypted the interaction network of hepatitis C virus proteins in living human cells. Their findings will contribute to a better...
View ArticleRussian scientists develop algorithm for anti-aging remedy search
MIPT scientists have provided an algorithm which can help in the search for aging-suppressing drugs. The researchers, whose work is published in Frontiers in Genetics magazine, have compared gene...
View ArticleMolecule acts as umpire to make tough life-or-death calls
Researchers have demonstrated that an enzyme required for animal survival after birth functions like an umpire, making the tough calls required for a balanced response to signals that determine if...
View ArticleResearchers tie social behavior to activity in specific brain circuit
A team of Stanford University investigators has linked a particular brain circuit to mammals' tendency to interact socially. Stimulating this circuit—one among millions in the brain—instantly increases...
View ArticleTeam discovers key to preventing blindness and stroke devastation
Research led by Nicolas Bazan, MD, PhD, Boyd Professor, Ernest C. and Yvette C. Villere Chair of Retinal Degeneration Research, and Director of the Neuroscience Center of Excellence at LSU Health New...
View ArticleNew technique lets scientists see and study the interface where two cells touch
Interactions between brain cells hold the key to healthy brain function and cognition, but many of those interactions are notoriously difficult to study.
View ArticleTargeting gene interactions to kill tumor cells
(Medical Xpress)—A particular kind of genetic interaction called synthetic dosage lethality (SDL) is a promising avenue for future cancer treatment, according to a study reported in the Proceedings of...
View Article'Love hormone' helps produce 'bliss molecules' to boost pleasure of social...
The hormone oxytocin, which has been associated with interpersonal bonding, may enhance the pleasure of social interactions by stimulating production of marijuana-like neurotransmitters in the brain,...
View ArticleMouse study suggests autism is not just a disease of the brain
Autism spectrum disorders (ASDs) are characterized by impaired social interactions and repetitive behaviors, often accompanied by abnormal reactions to sensory stimuli. ASD is generally thought to be...
View ArticleLong noncoding RNA found to quell inflammation
A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School....
View ArticleResearchers identify interaction among proteins that cause cancer cells to...
Researchers at Mayo Clinic have identified an interaction among proteins that allows cancer cells to grow and metastasize. They say the discovery may play a role in developing a better understanding of...
View ArticleSide effects not a major problem for new class of breast cancer drugs
A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most...
View ArticleShifting protein networks in breast cancer may alter gene function
A given gene may perform a different function in breast cancer cells than in healthy cells due to changes in networks of interacting proteins, according to a new study published in PLOS Computational...
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